ARN-Trio Registry Highlights Major Shifts in Infliximab Biosimilar Use
Analysis of the American Rheumatology Network-Trio Health (ARN-Trio) registry finds a surge in new prescriptions for Merck’s Renflexis infliximab biosimilar. The ARN-Trio registry is the first rheumatology registry to combine pharmacy dispensing data with electronic medical records (EMR) to provide unparalleled real-world insights. ARN-Trio is the largest registry of biosimilar use in community rheumatology practice, and data from 5 large practices chosen for geographic variety reveal insightful trends in infliximab biosimilar use. Initially, the use of Pfizer’s Inflectra (infliximab-dyyb) followed by Merck’s Reflexis (infliximab abda) followed trajectories largely explained by the well-documented formulary restrictions and time to market challenges inherent